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Current position:Home > Products > 1H-Benzotriazole

CAS No.:95-14-7

Name: 1H-Benzotriazole

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 500mg/kg (500mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(11), Pg. 70, 1981.
mouse LD50 intraperitoneal 400mg/kg (400mg/kg)   Farmakologiya i Toksikologiya Vol. 41, Pg. 708, 1978.
Link to PubMed
mouse LD50 intravenous 238mg/kg (238mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952.
Link to PubMed
mouse LD50 oral 615mg/kg (615mg/kg)   National Technical Information Service. Vol. AD-A067-313,
rabbit LDLo skin 450mg/kg (450mg/kg)   National Technical Information Service. Vol. OTS0520182,
rat LC50 inhalation 1910mg/m3/3H (1910mg/m3) LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
National Technical Information Service. Vol. OTS0520637,
rat LD50 oral 560mg/kg (560mg/kg)   National Technical Information Service. Vol. OTS0516797,
rat LD50 skin > 1gm/kg (1000mg/kg)   National Technical Information Service. Vol. OTS0516745,

  1H-Benzotriazole (CAS NO.95-14-7) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: HarmfulXn,IrritantXi,FlammableF
Risk Statements: 20/22-36-52/53-5-36/37/38-20/21/22-11
R11:Highly flammable. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R20/22:Harmful by inhalation and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R36:Irritating to eyes. 
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-36/37-61-45-36/37/39-28A 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.


Standards and Recommendations:

 


Analytical Methods:

 


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