CAS No.:95-14-7
Name: 1H-Benzotriazole
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 500mg/kg (500mg/kg) | AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(11), Pg. 70, 1981. |
mouse | LD50 | intraperitoneal | 400mg/kg (400mg/kg) | Farmakologiya i Toksikologiya Vol. 41, Pg. 708, 1978. Link to PubMed |
|
mouse | LD50 | intravenous | 238mg/kg (238mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952. Link to PubMed |
|
mouse | LD50 | oral | 615mg/kg (615mg/kg) | National Technical Information Service. Vol. AD-A067-313, | |
rabbit | LDLo | skin | 450mg/kg (450mg/kg) | National Technical Information Service. Vol. OTS0520182, | |
rat | LC50 | inhalation | 1910mg/m3/3H (1910mg/m3) | LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
National Technical Information Service. Vol. OTS0520637, |
rat | LD50 | oral | 560mg/kg (560mg/kg) | National Technical Information Service. Vol. OTS0516797, | |
rat | LD50 | skin | > 1gm/kg (1000mg/kg) | National Technical Information Service. Vol. OTS0516745, |
1H-Benzotriazole (CAS NO.95-14-7) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xn,Xi,F
Risk Statements: 20/22-36-52/53-5-36/37/38-20/21/22-11
R11:Highly flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R20/22:Harmful by inhalation and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36:Irritating to eyes.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-36/37-61-45-36/37/39-28A
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
Standards and Recommendations:
Analytical Methods:
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