CAS No.:675-20-7

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	subcutaneous	3gm/kg (3000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) CARDIAC: OTHER CHANGES	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
mouse	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Journal of Pharmaceutical Sciences. Vol. 60, Pg. 1058, 1971.
mouse	LD50	intravenous	600mg/kg (600mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 93, Pg. 143, 1953.
rat	LD50	intravenous	> 3gm/kg (3000mg/kg)		United States Patent Document. Vol. #3380887,
rat	LDLo	oral	11gm/kg (11000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	National Technical Information Service. Vol. OTS0571235,

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Moderately toxic by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: Xi
Risk Statements: 36/37-36/37/38
R36/37:Irritating to eyes and respiratory system. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26-36
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S37/39:Wear suitable gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 3
F: 3-10
HS Code: 29337900

Standards and Recommendations：

 

Analytical Methods：