CAS No.:1003-40-3
Name: 4-Aminopyridine hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | 2377mg/kg (2377mg/kg) | Journal of Wildlife Management. Vol. 29, Pg. 830, 1965. | |
mouse | LD50 | subcutaneous | 11900ug/kg (11.9mg/kg) | Eksperimentalna Meditsina i Morfologiya. Vol. 18, Pg. 98, 1979. | |
pig | LD50 | oral | 3547mg/kg (3547mg/kg) | Journal of Wildlife Management. Vol. 29, Pg. 830, 1965. | |
rabbit | LDLo | skin | 327mg/kg (327mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 93, 1969. | |
rat | LD50 | intravenous | 6700ug/kg (6.7mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 236, Pg. 149, 1959. | |
rat | LD50 | oral | 32mg/kg (32mg/kg) | Pest Control. Vol. 33, Pg. 16, 1965. | |
rat | LD50 | subcutaneous | 10130ug/kg (10.13mg/kg) | Eksperimentalna Meditsina i Morfologiya. Vol. 18, Pg. 98, 1979. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, skin contact and subcutaneous routes. An eye irritant. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Standards and Recommendations:
Analytical Methods:
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