CAS No.:99-96-7
Name: 4-Hydroxybenzoic acid
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 210mg/kg (210mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956. |
mouse | LD50 | oral | 2200mg/kg (2200mg/kg) | Drug Standards. Vol. 20, Pg. 89, 1952. | |
mouse | LD50 | subcutaneous | 1050mg/kg (1050mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 128, Pg. 135, 1960. | |
rat | LD50 | intraperitoneal | 340mg/kg (340mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 85, 1986. |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(7), Pg. 53, 1984. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xi
Risk Statements: 36-36/37/38
R36:Irritating to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
Standards and Recommendations:
Analytical Methods:
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