CAS No.:827-61-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	78mg/kg (78mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ANALGESIA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 189, Pg. 295, 1971.
mouse	LD50	intravenous	36mg/kg (36mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Russian Pharmacology and Toxicology Vol. 35, Pg. 55, 1972.
mouse	LD50	oral	165mg/kg (165mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 320, 1968.
mouse	LD50	subcutaneous	102mg/kg (102mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 320, 1968.
rat	LD50	intravenous	45mg/kg (45mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 320, 1968.
rat	LD50	subcutaneous	225mg/kg (225mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 320, 1968.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.

Standards and Recommendations：

 

Analytical Methods：