CAS No.:33089-61-1

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	100mg/kg (100mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 22, 1978.
duck	LD50	oral	7gm/kg (7000mg/kg)		Pesticide Manual. Vol. 9, Pg. 28, 1991.
guinea pig	LD50	oral	> 400mg/kg (400mg/kg)		Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
man	TDLo	oral	3571mg/kg (3571mg/kg)	BEHAVIORAL: ATAXIA BEHAVIORAL: COMA CARDIAC: PULSE RATE	Human & Experimental Toxicology. Vol. 16, Pg. 600, 1997.
mouse	LD50	oral	1085mg/kg (1085mg/kg)		Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (4), Pg. 36, 1995.
quail	LD50	oral	788mg/kg (788mg/kg)		Farm Chemicals Handbook. Vol. -, Pg. C20, 1991.
rabbit	LD50	oral	> 100mg/kg (100mg/kg)		Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rabbit	LD50	skin	> 200mg/kg (200mg/kg)		Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat	LC50	inhalation	65gm/m3/6H (65000mg/m3)		Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat	LD50	intraperitoneal	800mg/kg (800mg/kg)		Defense des Vegetaux. Vol. 33, Pg. 66, 1979.
rat	LD50	oral	400mg/kg (400mg/kg)		"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 80, 1989.
rat	LD50	skin	> 1600mg/kg (1600mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 22, 1978.
rat	LD50	unreported	600mg/kg (600mg/kg)		Japanese Journal of Toxicology. Vol. 2, Pg. 289, 1989.
rat	LDLo	intramuscular	250mg/kg (250mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Veterinary and Human Toxicology. Vol. 41, Pg. 355, 1999.
women	LDLo	oral	200uL/kg (0.2mL/kg)	BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES CARDIAC: OTHER CHANGES KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	American Journal of Emergency Medicine. Vol. 6, Pg. 510, 1988.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Amitraz (CAS NO.33089-61-1):
Hazard Codes: N,Xn
Risk Statements: 22-43-48/22-50/53 
22:  Harmful if swallowed 
43:  May cause sensitization by skin contact 
48:  Danger of serious damage to health by prolonged exposure 
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 22-24-36/37-60-61
22:  Do not breathe dust 
24:  Avoid contact with skin
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

Standards and Recommendations：

 

Analytical Methods：