CAS No.:68302-57-8
Name: Amlexanox
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 450mg/kg (450mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
| mouse | LD50 | oral | 2320mg/kg (2320mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
| mouse | LD50 | subcutaneous | 3310mg/kg (3310mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
| rat | LD50 | intraperitoneal | 500mg/kg (500mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
| rat | LD50 | oral | 10gm/kg (10000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
| rat | LD50 | subcutaneous | 1400mg/kg (1400mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 6405, 1985. |
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Analytical Methods：
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