CAS No.:538-03-4
Name: Arsphenoxide
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
ivn-hmn TDLo:400 µg/kg:CNS,BRN |
AJSGA3 American Journal of Syphilis, Gonorrhea and Venereal Diseases. 28 (1944),218. | ||
2. |
orl-rat LDLo:500 mg/kg |
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),12. | ||
3. |
ivn-rat LD50:18,500 µg/kg |
JACSAT Journal of the American Chemical Society. 70 (1948),1762. | ||
4. |
orl-mus LD50:110 µg/kg |
CLDND* Compilation of LD50 Values of New Drugs. 81 (1944),284. | ||
5. |
scu-mus LD50:25 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 81 (1944),284. | ||
6. |
ivn-mus LD50:20 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 81 (1944),284. | ||
7. |
ivn-dog LDLo:12 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 50 (1934),198. |
Consensus Reports:
Arsenic and its compounds are on the Community Right-To-Know List.
SAFETY PROFILE:
Poison by ingestion, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: stroke, convulsions, and coma. See also ARSENIC COMPOUNDS. When heated to decomposition it emits very toxic fumes of As, NOx, and HCl. An antirickettsial and antitrypanosomal agent.
Standards and Recommendations:
OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 μ (As)/L inorganic arsenic and methylated metabolites in urine
Analytical Methods:
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