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Current position:Home > Products > Arsphenoxide

CAS No.:538-03-4

Name: Arsphenoxide

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

ivn-hmn TDLo:400 µg/kg:CNS,BRN

    AJSGA3    American Journal of Syphilis, Gonorrhea and Venereal Diseases. 28 (1944),218.
2.    

orl-rat LDLo:500 mg/kg

    NCNSA6    National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),12.
3.    

ivn-rat LD50:18,500 µg/kg

    JACSAT    Journal of the American Chemical Society. 70 (1948),1762.
4.    

orl-mus LD50:110 µg/kg

    CLDND*    Compilation of LD50 Values of New Drugs. 81 (1944),284.
5.    

scu-mus LD50:25 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 81 (1944),284.
6.    

ivn-mus LD50:20 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 81 (1944),284.
7.    

ivn-dog LDLo:12 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 50 (1934),198.

Consensus Reports:

Arsenic and its compounds are on the Community Right-To-Know List.


SAFETY PROFILE:

Poison by ingestion, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: stroke, convulsions, and coma. See also ARSENIC COMPOUNDS. When heated to decomposition it emits very toxic fumes of As, NOx, and HCl. An antirickettsial and antitrypanosomal agent.


Standards and Recommendations:

OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 μ (As)/L inorganic arsenic and methylated metabolites in urine


Analytical Methods:

 


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