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CAS No.:146-36-1

Name: Azapetine

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 50mg/kg (50mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 intramuscular 600mg/kg (600mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 intraperitoneal 210mg/kg (210mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 intravenous 27mg/kg (27mg/kg)   Compilation of LD50 Values of New Drugs.
mouse LD50 oral 460mg/kg (460mg/kg)   Bollettino Chimico Farmaceutico. Vol. 98, Pg. 702, 1959.
mouse LD50 subcutaneous 725mg/kg (725mg/kg)   Compilation of LD50 Values of New Drugs.
rabbit LD50 intravenous 26mg/kg (26mg/kg)   Compilation of LD50 Values of New Drugs


Consensus Reports:

 


SAFETY PROFILE:

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion, subcutaneous, and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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