CAS No.:115-02-6

TOXICITY DATA with REFERENCE：

1.		mma-sat 200 ng/plate		PNASA6    Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),5135.
2.		mmo-bcs 500 µmol/L		EXPEAM    Experientia. 39 (1983),530.
3.		orl-rat LD50:170 mg/kg		CANCAR    Cancer. 10 (1957),889.
4.		ipr-rat LD50:70 mg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 94 (1957),27.
5.		orl-mus LD50:150 mg/kg		CANCAR    Cancer. 10 (1957),889.
6.		ipr-mus LD50:100 mg/kg		CANCAR    Cancer. 10 (1957),889.
7.		scu-mus LD50:50 mg/kg		85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 4 (1)(1980),432.
8.		ivn-mus LD50:62 mg/kg		85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1249.
9.		ivn-dog LDLo:30 mg/kg		TXAPA9    Toxicology and Applied Pharmacology. 22 (1972),595.

Consensus Reports：

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 (1976),p. 73.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

SAFETY PROFILE：

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
 

Hazard Codes: T
Risk Statements:
25:  Toxic if swallowed
40:  Limited evidence of a carcinogenic effect
Safety Statements:
36:  Wear suitable protective clothing 
37:  Wear suitable gloves
39:  Wear eye/face protection
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53:  Avoid exposure - obtain special instruction before use

Standards and Recommendations：

 

Analytical Methods：