CAS No.:
Name: BENZENEHEXACHLORIDE (mixed isomers)
Details Introduction
TOXICITY DATA with REFERENCE:
1. | unr-man TDLo:643 µg/kg:CNS | CMEP** Clinical Memoranda on Economic Poisons US Dept. HEW, Public Health Service, Communicable Disease Center,Atlanta, GA.: 1956,1. | ||
2. | orl-rat LD50:400 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow.: USSR, Centre of International Projects, GKNT,1982,73. | ||
3. | orl-mus LD50:500 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow.: USSR, Centre of International Projects, GKNT,1982,73. | ||
4. | orl-cat LDLo:300 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow.: USSR, Centre of International Projects, GKNT,1982,73. | ||
5. | ihl-cat LCLo:20 mg/m3/6H | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow.: USSR, Centre of International Projects, GKNT,1982,73. |
Consensus Reports:IARC Cancer Review: Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man , 5 (1974),p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man , 20 (1979),p. 195.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Confirmed carcinogen with experimental tumorigenic and neoplastigenic data. Poison by inhalation and ingestion. Human systemic effects by an unspecified route: convulsions. Potentially dangerous reaction with DMF in presence of Fe, also CCl4. When heated to decomposition it emits highly toxic fumes of Cl−, HCl, and phosgene. See also BENZENE HEXACHLORIDE and other benzenehexachloride entries.
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