CAS No.:3624-96-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 470mg/kg (470mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	"A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946Vol. 1, Pg. 304, 1946.
human	TDLo	oral	43mg/kg (43mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	"A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946Vol. 1, Pg. 304, 1946.
human	TDLo	oral	243mg/kg/9D (243mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	"A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946Vol. 1, Pg. 304, 1946.
mouse	LD50	oral	3950mg/kg (3950mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Antibiotics and Chemotherapy Vol. 7, Pg. 113, 1957.
rat	LD50	oral	1649mg/kg (1649mg/kg)		Antibiotics and Chemotherapy Vol. 7, Pg. 113, 1957.

Consensus Reports：

 

SAFETY PROFILE：

Poison to humans by ingestion with systemic effects: fever and nausea or vomiting. When heated to decomposition it emits toxic fumes of NO_x and HCl. See also ALLYL COMPOUNDS.

Standards and Recommendations：

 

Analytical Methods：