CAS No.:101-99-5
Name: Carbanilic Acid Ethyl Ester
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 350mg/kg (350mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 45, 1959. | |
mouse | LD50 | intravenous | 400mg/kg (400mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 45, 1959. | |
mouse | LDLo | subcutaneous | 1gm/kg (1000mg/kg) | behavioral: somnolence (general depressed activity) | "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933. |
rat | LDLo | unreported | 500mg/kg (500mg/kg) | behavioral: somnolence (general depressed activity) vascular: regional or general arteriolar or venous dilation | British Journal of Pharmacology and Chemotherapy. Vol. 7, Pg. 142, 1952. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Poison by intraperitoneal and intravenous routes. Moderately toxic by subcutaneous and possibly other routes. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.
Hazard Codes:
Xn
Risk Statements:
R40:Limited evidence of a carcinogenic effect.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves.
RTECS: FD8925000
Standards and Recommendations:
Analytical Methods:
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