CAS No.:630-08-0

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LC50	inhalation	1334ppm (1334ppm)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
dog	LCLo	inhalation	4000ppm/46M (4000ppm)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1360, 1935.
guinea pig	LC50	inhalation	5718ppm/4H (5718ppm)		Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.
human	LCLo	inhalation	4mg/m3/12H (4mg/m3)	BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	Toksikologicheskii Vestnik. Vol. (4), Pg. 26, 1999.
human	LCLo	inhalation	5000ppm/5M (5000ppm)		Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
human	TCLo	inhalation	600mg/m3/10M (600mg/m3)	BEHAVIORAL: HEADACHE	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(4), Pg. 34, 1987.
mammal (species unspecified)	LCLo	inhalation	5000ppm/5M (5000ppm)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.
man	LCLo	inhalation	4000ppm/30M (4000ppm)		"Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 207, 1968.
man	TCLo	inhalation	650ppm/45M (650ppm)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS	American Industrial Hygiene Association Journal. Vol. 34, Pg. 212, 1973.
mouse	LC50	inhalation	2444ppm/4H (2444ppm)		Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.
rabbit	LCLo	inhalation	4000ppm (4000ppm)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1360, 1935.
rat	LC50	inhalation	1807ppm/4H (1807ppm)		Toxicology and Applied Pharmacology. Vol. 17, Pg. 752, 1970.

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Hazard Codes: F+,T
Risk Statements: 61-12-23-48/23 
R61:May cause harm to the unborn child. 
R12:Extremely flammable. 
R23 :Toxic by inhalation. 
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 53-45 
S53:Avoid exposure - obtain special instructions before use. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1016 2.3
WGK Germany: 1
RTECS of Carbon monoxide (CAS NO.630-08-0): FG3500000

Standards and Recommendations：

OSHA PEL: TWA 35 ppm; CL 200 ppm
ACGIH TLV: 25 ppm; BEI: 3% of hemoglobin indicating carboxyhemoglobin in blood at end of shift; 20 ppm CO in end-exhaled air at end of shift.
DFG MAK: 30 ppm (35 mg/m³); BAT: 5% carboxyhemoglobin in blood at end of shift
NIOSH REL: (Carbon Monoxide) TWA 35 ppm; CL 200 ppm
DOT Classification:  2.3; Label: Poison Gas, Flammable Gas

Analytical Methods：

For occupational chemical analysis use NIOSH: Carbon Monoxide S340.