CAS No.:5913-76-8
Name: Codeine phosphate sesquihydrate
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
orl-rat LD50:209 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1011. | ||
2. |
ipr-rat LD50:38 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1011. | ||
3. |
scu-rat LD50:81 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1011. | ||
4. |
orl-mus LD50:290 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1787. | ||
5. |
ipr-mus LD50:83 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1011. | ||
6. |
scu-mus LD50:191 mg/kg |
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. 81 (1961),740. | ||
7. |
ivn-mus LD50:70 mg/kg |
KSRNAM Kiso to Rinsho. Clinical Report. 5 (1971),1787. | ||
8. |
ivn-dog LD50:97,800 µg/kg |
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. 81 (1961),740. | ||
9. |
orl-rbt LDLo:100 mg/kg |
MEIEDD Merck Index. 10 (1983),350. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and POx. A narcotic analgesic and antitussive. See also CODEINE and CODEINE PHOSPHATE.
Standards and Recommendations:
Analytical Methods:
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