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Current position:Home > Products > Codeine phosphate sesquihydrate

CAS No.:5913-76-8

Name: Codeine phosphate sesquihydrate

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:209 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1011.
2.    

ipr-rat LD50:38 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1011.
3.    

scu-rat LD50:81 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1011.
4.    

orl-mus LD50:290 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1787.
5.    

ipr-mus LD50:83 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1011.
6.    

scu-mus LD50:191 mg/kg

    YKKZAJ    Yakugaku Zasshi. Journal of Pharmacy. 81 (1961),740.
7.    

ivn-mus LD50:70 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1787.
8.    

ivn-dog LD50:97,800 µg/kg

    YKKZAJ    Yakugaku Zasshi. Journal of Pharmacy. 81 (1961),740.
9.    

orl-rbt LDLo:100 mg/kg

    MEIEDD    Merck Index. 10 (1983),350.

Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and POx. A narcotic analgesic and antitussive. See also CODEINE and CODEINE PHOSPHATE.


Standards and Recommendations:

 


Analytical Methods:

 


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