CAS No.:61-12-1

TOXICITY DATA with REFERENCE：

1.		eye-rbt 2% SEV		ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),181.
2.		dnd-esc 15 µmol/L		MUREAV    Mutation Research. 89 (1981),95.
3.		ipr-rat LD50:30 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 103 (1951),306.
4.		scu-rat LD50:27 mg/kg		DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.: )1990,478.
5.		ivn-rat LD50:52 mg/kg		DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.: )1990,478.
6.		ipr-mus LD50:29 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 94 (1948),299.
7.		scu-mus LD50:25,400 µg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 103 (1960),353.
8.		ivn-mus LD50:5151 µg/kg		JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 44 (1955),393.
9.		scu-rbt LDLo:5 mg/kg		ODFU**    Vergleichende pharmakologische Prufung Zweier neuer Lokalanas-thetika: Perkain und Pantokain, Wilhelm Ost Dissertation .(Pharmakologischen Institut der Universitat zu Frankfurt am Ma

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, subcutaneous, intravenous, intraspinal, parenteral, and intraperitoneal routes. Mutation data reported. A severe eye irritant. A local anesthetic. When heated to decomposition it emits very toxic fumes of HCl and NO_x
Safety Information of Dibucaine Hydrochloride (CAS NO.61-12-1):
Hazard Codes: Xn
Xn: Harmful 
Risk Statements: 22-41
22: Harmful if swallowed 
41: Risk of serious damage to eyes 
Safety Statements: 26-39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
39: Wear eye/face protection 
WGK Germany: 3
RTECS: GD3325000

Standards and Recommendations：

 

Analytical Methods：