CAS No.:3521-62-8
Name: Erythromycin estolate
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | > 6450mg/kg (6450mg/kg) | Drugs in Japan Vol. -, Pg. 211, 1990. | |
mouse | LD50 | subcutaneous | > 6450mg/kg (6450mg/kg) | Drugs in Japan Vol. -, Pg. 211, 1990. | |
rat | LD50 | oral | 1447mg/kg (1447mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
rat | LD50 | subcutaneous | > 6450mg/kg (6450mg/kg) | Drugs in Japan Vol. -, Pg. 211, 1990. | |
women | TDLo | unreported | 100mg/kg/5D-I (100mg/kg) | LIVER: CHANGE IN GALL BLADDER STRUCTURE OR FUNCTION | Clinical Pharmacology and Therapeutics Vol. 6, Pg. 788, 1965. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xn,
Xi
Risk Statements: 22-42/43-36/37/38
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-36-26
S22:Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
Standards and Recommendations:
Analytical Methods:
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