CAS No.:11111-23-2
Name: Lividomycin
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intramuscular | 1348mg/kg (1348mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
| mouse | LD50 | intravenous | 225mg/kg (225mg/kg) | SENSE ORGANS AND SPECIAL SENSES: "RETINAL CHANGES (PIGMENTARY DEPOSITIONS, RETINITIS, OTHER): EYE" BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. | |
| mouse | LD50 | subcutaneous | 1249mg/kg (1249mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
| rat | LD50 | intramuscular | 1750mg/kg (1750mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
| rat | LD50 | intravenous | 365mg/kg (365mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. | |
| rat | LD50 | subcutaneous | 1819mg/kg (1819mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 787, 1972. |
Consensus Reports：
SAFETY PROFILE：
Standards and Recommendations：
Analytical Methods：
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