CAS No.:3771-19-5
Name: Melipan
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
dns-rat:lvr 10 mg/L |
CRNGDP Carcinogenesis. 5 (1984),1033. | ||
2. |
dni-mus:oth 100 µmol/L |
CNREA8 Cancer Research. 40 (1980),36. | ||
3. |
orl-rat TDLo:39 g/kg/92W-C:CAR |
JNCIAM Journal of the National Cancer Institute. 59 (1977),1645. | ||
4. |
orl-mus TDLo:56 g/kg/81W-C:CAR |
CNREA8 Cancer Research. 36 (1976),1211. | ||
5. |
orl-rat TD:33 g/kg/78W-C:ETA |
CNREA8 Cancer Research. 36 (1976),1211. | ||
6. |
orl-rat LD50:900 mg/kg |
TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. |
Consensus Reports:
IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 ,1980,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 ,1980,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. A drug for the treatment of hypercholesterolemia or hypertriglyceridemia. When heated to decomposition it emits acrid smoke and irritating fumes.
Standards and Recommendations:
Analytical Methods:
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