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Current position:Home > Products > Methylergonovine maleate salt

CAS No.:57432-61-8

Name: Methylergonovine maleate salt

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 6mg/kg (6mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 85mg/kg (85mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
mouse LD50 oral 187mg/kg (187mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rabbit LD50 intravenous 2600ug/kg (2.6mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rat LD50 intravenous 23mg/kg (23mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
rat LD50 oral 93mg/kg (93mg/kg)   Drugs in Japan Vol. 6, Pg. 828, 1982.
women TDLo oral 36ug/kg/3D-I (0.036mg/kg) CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION

CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
American Journal of Emergency Medicine. Vol. 16, Pg. 502, 1998.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, intravenous, and intraperitoneal routes. Human teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Methylergonovine maleate (CAS NO.57432-61-8):
Hazard Codes: T
Risk Statements: 23/24/25-62 
23:  Toxic by inhalation 
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
62:  Possible risk of impaired fertility
Safety Statements: 36/37/39-45
36:  Wear suitable protective clothing  
37:  Wear suitable gloves
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)


Standards and Recommendations:

 


Analytical Methods:

 


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