CAS No.:615-53-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
hamster	LDLo	subcutaneous	21mg/kg (21mg/kg)		American Journal of Pathology. Vol. 50, Pg. 639, 1967.
mammal (species unspecified)	LD50	intravenous	4mg/kg (4mg/kg)		Gann Monograph on Cancer Research. Vol. 17, Pg. 107, 1975.
mammal (species unspecified)	LD50	oral	240mg/kg (240mg/kg)		Gann Monograph on Cancer Research. Vol. 17, Pg. 107, 1975.
mouse	LCLo	inhalation	600mg/m3/10M (600mg/m3)		National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. MAR1942,
mouse	LD50	intraperitoneal	37mg/kg (37mg/kg)		Cancer Research. Vol. 30, Pg. 11, 1970.
mouse	LDLo	subcutaneous	7mg/kg (7mg/kg)		British Journal of Cancer. Vol. 23, Pg. 167, 1969.
rat	LD50	intravenous	4mg/kg (4mg/kg)		Zeitschrift fuer Krebsforschung. Vol. 69, Pg. 103, 1967.
rat	LD50	oral	180mg/kg (180mg/kg)		Naturwissenschaften. Vol. 48, Pg. 165, 1961.
rat	LDLo	intraperitoneal	50mg/kg (50mg/kg)		British Journal of Cancer. Vol. 22, Pg. 316, 1968.
rat	LDLo	subcutaneous	125mg/kg (125mg/kg)		British Journal of Cancer. Vol. 16, Pg. 92, 1962.

Consensus Reports：

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 211.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

SAFETY PROFILE：

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Experimental reproductive effects. Mutation data reported. Has been implicated as a transplacental brain carcinogen. Combustible when exposed to heat, sparks, open flame, and powerful oxidizers. Explodes when heated. A storage hazard. When heated to decomposition it emits toxic fumes of NO_x. See also NITROSAMINES and CARBAMATES.

Risk Statements 5-36/37/38-40
R5 : Heating may cause an explosion. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R40: Limited evidence of a carcinogenic effect.
Safety Statements 23-35-45-53
S23: Do not breathe vapour. 
S35: This material and its container must be disposed of in a safe way. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53: Avoid exposure - obtain special instructions before use.
RIDADR: 2810
RTECS: FC6300000
HazardClass: 1.1A
PackingGroup: I

Standards and Recommendations：

 

Analytical Methods：