CAS No.:73080-51-0
Name: Repirinast
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD | oral | > 5gm/kg (5000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 577, 1986. | |
mouse | LD50 | intraperitoneal | 1435mg/kg (1435mg/kg) | GASTROINTESTINAL: PERITONITIS KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
mouse | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
rabbit | LDLo | oral | > 5gm/kg (5000mg/kg) | LIVER: OTHER CHANGES BLOOD: CHANGES IN SPLEEN KIDNEY, URETER, AND BLADDER: CHANGES PRIMARILY IN GLOMERULI |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
rat | LD50 | intraperitoneal | 2783mg/kg (2783mg/kg) | GASTROINTESTINAL: PERITONITIS KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
rat | LD50 | oral | > 5gm/kg (5000mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | BEHAVIORAL: FOOD INTAKE (ANIMAL) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986. |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
Standards and Recommendations:
Analytical Methods:
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