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Current position:Home > Products > Repirinast

CAS No.:73080-51-0

Name: Repirinast

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 5gm/kg (5000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 577, 1986.
mouse LD50 intraperitoneal 1435mg/kg (1435mg/kg) GASTROINTESTINAL: PERITONITIS

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
mouse LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL) Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
rabbit LDLo oral > 5gm/kg (5000mg/kg) LIVER: OTHER CHANGES

BLOOD: CHANGES IN SPLEEN

KIDNEY, URETER, AND BLADDER: CHANGES PRIMARILY IN GLOMERULI
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
rat LD50 intraperitoneal 2783mg/kg (2783mg/kg) GASTROINTESTINAL: PERITONITIS

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
rat LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL) Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 545, 1986.


Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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