CAS No.:10453-86-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	75mg/kg (75mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
dog	LC	inhalation	> 420mg/m3/4H (420mg/m3)		National Technical Information Service. Vol. AD747-345,
dog	LDLo	intravenous	250mg/kg (250mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	National Technical Information Service. Vol. AD747-345,
mammal (species unspecified)	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mammal (species unspecified)	LD50	oral	> 3375mg/kg (3375mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mouse	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)	PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mouse	LD50	oral	300mg/kg (300mg/kg)		Agricultural and Biological Chemistry. Vol. 37, Pg. 2681, 1973.
mouse	LD50	skin	> 5gm/kg (5000mg/kg)		Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
mouse	LD50	subcutaneous	> 2gm/kg (2000mg/kg)		Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
rabbit	LD50	skin	2500mg/kg (2500mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 9, 1978.
rabbit	LDLo	intravenous	250mg/kg (250mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: IRRITABILITY	National Technical Information Service. Vol. AD747-345,
rat	LC	inhalation	> 420mg/m3/4H (420mg/m3)		National Technical Information Service. Vol. AD747-345,
rat	LD50	oral	1244mg/kg (1244mg/kg)		Fundamental and Applied Toxicology. Vol. 7, Pg. 299, 1986.
rat	LD50	skin	3gm/kg (3000mg/kg)		Yakkyoku. Pharmacy. Vol. 38, Pg. 1331, 1987.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)		Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
rat	LDLo	intraperitoneal	19200mg/kg (19200mg/kg)		National Technical Information Service. Vol. AD747-345,
rat	LDLo	intravenous	160mg/kg (160mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Biologico. Vol. 41, Pg. 283, 1975.

Consensus Reports：

EPA FIFRA 1988 pesticide subject to registration or re-registration. EPA Genetic Toxicology Program.

SAFETY PROFILE：

Poison by ingestion, and intravenous routes. Moderately toxic by inhalation and skin contact. When heated to decomposition it emits acrid and irritating fumes. See also ESTERS.
Safety Information of Resmethrin (CAS NO.10453-86-8):
Hazard Codes: Xn,N
Risk Statements: 22-50/53 
22:  Harmful if swallowed
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 60/61-61-60
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

Standards and Recommendations：

 

Analytical Methods：