CAS No.:60084-10-8
Name: Riboxamide
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
dni-mus:lym 10 µmol/L |
CNREA8 Cancer Research. 45 (1985),5512. | ||
2. |
dni-mus:leu 10 µmol/L |
BCPCA6 Biochemical Pharmacology. 34 (1985),1109. | ||
3. |
ivn-hmn TDLo:1135 mg/kg/15D-I:CNS,MSK |
CNREA8 Cancer Research. 45 (1985),5169. | ||
4. |
ivn-hmn TDLo:892 mg/kg/10D-I:CNS |
CNREA8 Cancer Research. 45 (1985),5169. | ||
5. |
ipr-mus LD50:1684 mg/kg |
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . | ||
6. |
ivn-mus LD50:3400 mg/kg |
NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 . | ||
7. |
ivn-dog LDLo:1090 mg/kg |
NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 . |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by intravenous route: headache, convulsions, and musculo-skeletal changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
Standards and Recommendations:
Analytical Methods:
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