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Current position:Home > Products > Riboxamide

CAS No.:60084-10-8

Name: Riboxamide

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

dni-mus:lym 10 µmol/L

    CNREA8    Cancer Research. 45 (1985),5512.
2.    

dni-mus:leu 10 µmol/L

    BCPCA6    Biochemical Pharmacology. 34 (1985),1109.
3.    

ivn-hmn TDLo:1135 mg/kg/15D-I:CNS,MSK

    CNREA8    Cancer Research. 45 (1985),5169.
4.    

ivn-hmn TDLo:892 mg/kg/10D-I:CNS

    CNREA8    Cancer Research. 45 (1985),5169.
5.    

ipr-mus LD50:1684 mg/kg

    NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
6.    

ivn-mus LD50:3400 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 .
7.    

ivn-dog LDLo:1090 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 .

Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by intravenous route: headache, convulsions, and musculo-skeletal changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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