CAS No.:102-76-1

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	1500mg/kg (1500mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
frog	LDLo	oral	150mg/kg (150mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
guinea pig	LDLo	intramuscular	1740mg/kg (1740mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 76, Pg. 189, 1942.
mouse	LD50	intraperitoneal	1400mg/kg (1400mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: STIFFNESS	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963.
mouse	LD50	intravenous	1600mg/kg (1600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Acta Physiologica Scandinavica. Vol. 40, Pg. 338, 1957.
mouse	LD50	oral	1100mg/kg (1100mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: STIFFNESS	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 22, Pg. 368, 1963.
mouse	LD50	subcutaneous	2300mg/kg (2300mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941.
rabbit	LD50	intravenous	750mg/kg (750mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
rat	LD50	intraperitoneal	2100mg/kg (2100mg/kg)		Food and Cosmetics Toxicology. Vol. 16, Pg. 879, 1978.
rat	LD50	oral	3gm/kg (3000mg/kg)		AMA Archives of Industrial Health. Vol. 21, Pg. 28, 1960.
rat	LD50	subcutaneous	2800mg/kg (2800mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Proceedings of the Society for Experimental Biology and Medicine. Vol. 46, Pg. 26, 1941.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Triacetin (CAS NO.102-76-1):
Safety Statements: 23-24/25
23:  Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) 
24:  Avoid contact with skin 
25:  Avoid contact with eyes 

Standards and Recommendations：

 

Analytical Methods：