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AdreView (iobenguane I-123) belongs to a group of drugs called diagnostic radiopharmaceuticals (RAY dee oh far ma SOO tik als). AdreView is a radioactive agent that allows images of specific organs in the body to be detected by a gamma camera.

AdreView is used to detect certain kinds of cancer of the adrenal glands

AdreView may also be used for purposes not listed in this medication guide.

Important information

You should not receive AdreView if you are allergic to iobenguane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to potassium.

Before you are treated with AdreView, tell your doctor if you have kidney disease, a thyroid disorder, if you are dehydrated or unable to urinate, or if you are allergic to iodine.

Tell your doctor about all other medications you are using, especially antidepressants, cold medicines, blood pressure medications, or ADHD medications. You may need to stop using certain drugs for a short time before you receive AdreView

Drink extra fluids before you receive AdreView, and for at least 48 hours afterward. Follow your doctor"s instructions about the types and amount of liquids you should drink before and after your test. AdreView is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination. Do not allow yourself to become dehydrated during the first few days after receiving AdreView. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor"s instructions about the types and amount of fluids you should drink.

Before receiving AdreView

You should not receive AdreView if you are allergic to iobenguane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to potassium.

To make sure you can safely receive AdreView, tell your doctor if you have any of these other conditions:

• kidney disease;

• a thyroid disorder;

• if you are dehydrated or unable to urinate; or

• if you are allergic to iodine.

FDA pregnancy category C. It is not known whether AdreView will harm an unborn baby. Tell your doctor if you are pregnant before you are treated with AdreView. It is not known whether iobenguane I-123 passes into breast milk or if it could harm a nursing baby. Do not breast-feed within 6 days after receiving AdreView. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Older adults may need kidney function tests before receiving AdreView. Your kidney function may also need to be watched closely after you have received this medication.

How is AdreView given?

AdreView is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. It is usually given about 24 hours before your radiologic test.

At least 1 hour before you are treated with AdreView, you will be given a liquid drink that contains medicine to protect your thyroid from harmful radioactive effects of AdreView.

Drink extra fluids before you receive AdreView, and for at least 48 hours afterward. Follow your doctor"s instructions about the types and amount of liquids you should drink before and after your test. AdreView is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.

Expect to urinate often during the first 48 hours after your test. You will know you are getting enough extra fluid if you are urinating more than usual during this time. Urinating often will help rid your body of the radioactive iodine.

What happens if I miss a dose?

Since AdreView is used only given once before your radiologic test, you will not be on a daily dosing schedule. Call your doctor if for some reason you will not be able to complete your radiologic test within 24 hours after you receive your injection.

What happens if I overdose?

Since AdreView is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid?

Do not allow yourself to become dehydrated during the first few days after receiving AdreView. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor"s instructions about the types and amount of fluids you should drink.

AdreView side effects

Get emergency medical help if you have any of these signs of an allergic reaction to AdreView: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious AdreView side effects may include:

• dizziness;

• mild skin rash or itching;

• bleeding around your IV needle; or

• warmth, tingling, or cold feeling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect AdreView?

You may need to stop using certain drugs for a short time before you receive AdreView. Tell your doctor about all other medications you are using, especially:

• atomoxetine (Strattera);

• labetalol (Normodyne, Trandate);

• maprotiline (Ludiomil);

• reserpine;

• decongestant cold medicines, diet pills, and other stimulants;

• an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), amoxapine (Asendin), bupropion (Wellbutrin, Zyban), citalopram (Celexa), desipramine (Norpramin), doxepin (Sinequan), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), sertraline (Zoloft), and others; or

• street drugs, especially cocaine.

There may be other drugs that can affect AdreView. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.