DaTscan (ioflupane I-123) belongs to a group of drugs called diagnostic radiopharmaceuticals (RAY dee oh far ma SOO tik als). Ioflupane I-123 is a radioactive agent that allows images of the brain to be detected by a gamma camera.
DaTscan is used to detect brain signs of Parkinson"s disease in people with symptoms such as tremors, loss of balance or coordination, shuffling walk, or other movement problems.
DaTscan may also be used for purposes not listed in this medication guide.
Important information
You should not receive DaTscan if you have ever had any type of reaction to another contrast agent, or to iodine.
Before receiving this medicine
You should not receive DaTscan if you are allergic to ioflupane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to iodine.
To make sure DaTscan is safe for you, tell your doctor if you have:
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kidney disease;
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liver disease; or
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a thyroid disorder.
FDA pregnancy category C. It is not known whether DaTscan will harm an unborn baby. Tell your doctor if you are pregnant before receiving this medication.
See also: Pregnancy and breastfeeding warnings (in more detail)
It is not known whether ioflupane I-123 passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving DaTscan.
Older adults may need kidney function tests before receiving DaTscan. Your kidney function may also need to be watched closely after you have received this medication.
How is DaTscan given?
DaTscan is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. It is usually given about 3 to 6 hours before your radiologic test.
At least 1 hour before you are treated with DaTscan, you will be given a liquid drink that contains medicine to protect your thyroid from harmful radioactive effects of ioflupane I-123.
Drink plenty of liquid before you receive DaTscan, and for at least 48 hours afterward. Follow your doctor"s instructions about the types and amount of liquids you should drink before and after your test. Ioflupane I-123 is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.
Expect to urinate often during the first 48 hours after your test. You will know you are getting enough extra fluid if you are urinating more than usual during this time. Urinating often will help rid your body of the radioactive iodine.
What happens if I miss a dose?
Since DaTscan is used only given once before your radiologic test, you will not be on a daily dosing schedule. Call your doctor if for some reason you will not be able to complete your radiologic test within 3 to 6 hours after you receive your injection.
What happens if I overdose?
Since DaTscan is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid after receiving DaTscan?
Do not allow yourself to become dehydrated during the first few days after receiving DaTscan. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor"s instructions about the type and amount of liquids you should drink.
DaTscan side effects
Get emergency medical help if you have any of these signs of an allergic reaction to DaTscan: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Common DaTscan side effects may include:
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pain, swelling, burning, or irritation around the IV needle;
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headache;
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dizziness, spinning sensation;
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dry mouth; or
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nausea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect DaTscan?
You may need to stop using certain drugs for a short time before you receive DaTscan. Tell your doctor about all other medicines you use. Other drugs may interact with ioflupane I-123, including prescription and over-the-counter medicines, vitamins, and herbal products.
