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CAS No.:3564-66-7

Name: (+)-Trimipramine

Details Introduction

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	140mg/kg (140mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 307, 1961.
mouse	LD50	intravenous	38mg/kg (38mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 307, 1961.
mouse	LD50	oral	395mg/kg (395mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 307, 1961.
mouse	LD50	subcutaneous	415mg/kg (415mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 307, 1961.

Consensus Reports：

SAFETY PROFILE：

A poison by ingestion, intraperitoneal, and intravenous route. When heated to decomposition it emits toxic vapors of NO_x.

Standards and Recommendations：

Analytical Methods：