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Current position:Home > Products > 1-(1,3-Benzodioxol-5-yl)propan-2-amine hydrochloride

CAS No.:6292-91-7

Name: 1-(1,3-Benzodioxol-5-yl)propan-2-amine hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 7mg/kg (7mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
guinea pig LD50 intraperitoneal 28mg/kg (28mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
monkey LD50 intravenous 6mg/kg (6mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: REGIDITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
mouse LD50 intraperitoneal 68mg/kg (68mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
rat LD50 intraperitoneal 27mg/kg (27mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.


Consensus Reports:

 


SAFETY PROFILE:

Poison by intravenous and intraperitoneal routes. Mutagenic data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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