CAS No.:2192-21-4

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	50mg/kg (50mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
mouse	LD50	intraperitoneal	90mg/kg (90mg/kg)		Drugs in Japan Vol. -, Pg. 180, 1990.
mouse	LD50	intravenous	28mg/kg (28mg/kg)		Pharmaceutical Chemistry Journal Vol. 23, Pg. 966, 1989.
mouse	LD50	oral	352mg/kg (352mg/kg)		Drugs in Japan Vol. 6, Pg. 109, 1982.
mouse	LD50	subcutaneous	234mg/kg (234mg/kg)		Pharmaceutical Chemistry Journal Vol. 21, Pg. 646, 1987.
rat	LD50	intraperitoneal	66mg/kg (66mg/kg)		Drugs in Japan Vol. -, Pg. 180, 1990.
rat	LD50	intravenous	20800ug/kg (20.8mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
rat	LD50	oral	716mg/kg (716mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
rat	LD50	subcutaneous	1900mg/kg (1900mg/kg)		Drugs in Japan Vol. -, Pg. 180, 1990.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NO_x and HCl.

Standards and Recommendations：

 

Analytical Methods：