CAS No.:13909-13-2
Name: 1-(2-Chloroethyl)-1-nitroso-3-(2-norb-ornyl)urea
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 54760ug/kg (54.76mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
mouse | LD50 | oral | 56mg/kg (56mg/kg) | Progress Report Submitted to the National Cancer Institute by Mason Research Institute. Vol. -, Pg. 372, 1968. | |
rat | LD50 | oral | 83mg/kg (83mg/kg) | LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" | Progress Report Submitted to the National Cancer Institute by Mason Research Institute. Vol. -, Pg. 372, 1968. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also N-NITROSO COMPOUNDS.
Standards and Recommendations:
Analytical Methods:
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