CAS No.:76-11-9
Name: 1,1,1,2-Tetrachloro-2,2-difluoroethane
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LCLo | inhalation | 20000ppm/30M (20000ppm) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES |
Toxicology and Applied Pharmacology. Vol. 19, Pg. 1, 1971. |
rat | LD50 | oral | > 8gm/kg (8000mg/kg) | Nature. Vol. 210, Pg. 744, 1966. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Mildly toxic by inhalation. When heated to decomposition it emits very toxic fumes of Cl− and F−. Used as a refrigerant. See also Fluorides.Safety information of 1,1,1,2-Tetrachloro-2,2-difluoroethane (CAS NO.76-11-9):
Hazard Codes: N,Xi
Risk Statements
59 Dangerous for the ozone layer
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
59 Refer to manufacturer/supplier for information on recovery/recycling
37/39 Wear suitable gloves and eye/face protection
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Standards and Recommendations:
OSHA PEL: TWA 500 ppm
ACGIH TLV: TWA 500 ppm
DFG MAK: 1000 ppm (8500 mg/m3)
NIOSH REL: (1,1,1,2-Tetrachloro-2,2-difluoroethane) TWA 500 ppm
Analytical Methods:
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