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Current position:Home > Products > 1,1,3-Trimethyl-2-thiourea

CAS No.:2489-77-2

Name: 1,1,3-Trimethyl-2-thiourea

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

msc-mus:lyms 4200 mg/L

    EMMUEG    Environmental and Molecular Mutagenesis. 12 (1988),85.
2.    

orl-rat TDLo:13 g/kg/77W-C:CAR

    NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-129 ,1979.
3.    

orl-rat LD50:316 mg/kg

    NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 .
4.    

orl-mus LD50:215 mg/kg

    NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 .

Consensus Reports:

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-129 ,1979. . Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Poison by ingestion. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also ISOTHIOUREA.
Risk Statements about 1,1,3-Trimethyl-2-thiourea (CAS No.2489-77-2):
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about 1,1,3-Trimethyl-2-thiourea (CAS No.2489-77-2):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.


Standards and Recommendations:

 


Analytical Methods:

 


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