CAS No.:30652-11-0

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	oral	1gm/kg (1000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	BioMetals. Vol. 10, Pg. 247, 1997.
mammal (species unspecified)	LD50	unreported	> 1gm/kg (1000mg/kg)		Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996.
mouse	LD50	intraperitoneal	983mg/kg (983mg/kg)		Blood. Vol. 76, Pg. 2389, 1990.
rat	LD50	intraperitoneal	600mg/kg (600mg/kg)		Drugs of the Future. Vol. 13, Pg. 413, 1988.
rat	LD50	oral	2gm/kg (2000mg/kg)	CARDIAC: OTHER CHANGES	Archives of Toxicology, Supplement. Vol. 18, Pg. 202, 1996.

Consensus Reports：

 

SAFETY PROFILE：

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NO_x.
Hazard Codes:
Xn: Harmful
Risk Statements about 1,2-Dimethyl-3-hydroxy-4-pyridone (30652-11-0):
R22 Harmful if swallowed. 
R36/37/38 Irritating to eyes, respiratory system and skin. 
Safety Statements about 1,2-Dimethyl-3-hydroxy-4-pyridone (30652-11-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39 Wear suitable gloves and eye/face protection.
Attentions:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Standards and Recommendations：

 

Analytical Methods：