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Current position:Home > Products > 1,3,4,5,6,7,8,8-Octachloro-1,3,3a,4,7,7a-hexahydro-4,7-methanoisobenzofuran

CAS No.:297-78-9

Name: 1,3,4,5,6,7,8,8-Octachloro-1,3,3a,4,7,7a-hexahydro-4,7-methanoisobenzofuran

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 1mg/kg (1mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
cat LD50 oral 5mg/kg (5mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 556, 1969.
chicken LD50 oral 2000ug/kg (2mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
dog LD50 oral 1mg/kg (1mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
duck LD50 oral 1800ug/kg (1.8mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 556, 1969.
guinea pig LD50 oral 2000ug/kg (2mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
guinea pig LD50 skin 2mg/kg (2mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
hamster LD50 oral 7500ug/kg (7.5mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 556, 1969.
mouse LD50 intraperitoneal 8170ug/kg (8.17mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
mouse LD50 intravenous 2900ug/kg (2.9mg/kg)   Bochu Kagaku. Scientific Pest Control. Vol. 32, Pg. 46, 1967.
mouse LD50 oral 8400ug/kg (8.4mg/kg)   Journal of Economic Entomology. Vol. 65, Pg. 632, 1972.
pigeon LD50 oral 10ug/kg (0.01mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 4210ug/kg (4.21mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit LD50 oral 4mg/kg (4mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
rabbit LD50 skin 12mg/kg (12mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1099, 1966.
rat LD50 intraperitoneal 3560ug/kg (3.56mg/kg)   "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Ter Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970Vol. -, Pg. 88, 1970.
rat LD50 intravenous 1800ug/kg (1.8mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

ENDOCRINE: HYPERGLYCEMIA
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 232, Pg. 227, 1957.
rat LD50 oral 4800ug/kg (4.8mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 13, 1966.
rat LD50 skin 5mg/kg (5mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LD50 unreported 5mg/kg (5mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 397, 1971.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Used as an insecticide. When heated to decomposition it emits toxic fumes of Cl. See also CHLORINATED HYDROCARBONS, ALIPHATIC.Safety information of Isobenzan (CAS NO.297-78-9):
Hazard Codes  VeryT+,DangerousN
Risk Statements 
27/28 Very Toxic in contact with skin and if swallowed
50 Very Toxic to aquatic organisms
Safety Statements 
28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/37 Wear suitable protective clothing and gloves
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61 Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR  2761
RTECS  PC1225000
HazardClass  6.1(a)
PackingGroup  II


Standards and Recommendations:

 


Analytical Methods:

 


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