CAS No.:54-91-1
Name: 1,4-Bis-(3-bromo-1-oxopropyl)piperazine
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 285mg/kg (285mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 37, Pg. 249, 1980. | |
| mouse | LD50 | oral | 382mg/kg (382mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973. | |
| mouse | LD50 | subcutaneous | 353mg/kg (353mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973. | |
| rat | LD50 | intraperitoneal | 140mg/kg (140mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973. | |
| rat | LD50 | oral | 220mg/kg (220mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973. | |
| rat | LD50 | subcutaneous | 139mg/kg (139mg/kg) | Drugs in Japan Vol. 6, Pg. 638, 1982. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion, subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Br− and NOx. See also BROMIDES.
Standards and Recommendations：
Analytical Methods：
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