CAS No.:2243-62-1

TOXICITY DATA with REFERENCE：

1.		mma-sat 33,300 ng/plate		ENMUDM    Environmental Mutagenesis. 7 (Suppl 5)(1985),1.
2.		mma-sat 33,300 ng/plate		ENMUDM    Environmental Mutagenesis. 7 (Suppl 5)(1985),1.
3.		orl-rat TDLo:721 g/kg/1Y-C:CAR		IARC**    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (World Health Organization, Internation Agency for Research on Cancer, Lyon, France) 27 (1982),127.
4.		orl-rat TD:18 g/kg/88W-C:ETA,REP		NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-143 ,1978.
5.		orl-rat TDLo:54 g/kg/2Y-C:NEO		NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-143 ,1978.

Consensus Reports：

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 127.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-143 ,1978. . EPA Genetic Toxicology Program.

SAFETY PROFILE：

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic data. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES.
Hazard Codes:
Xn: Harmful
N: Dangerous for the environment
Risk Statements about 1,5-Naphthalenediamine (2243-62-1):
R40 Limited evidence of a carcinogenic effect. 
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
Safety Statements about 1,5-Naphthalenediamine (2243-62-1):
S36/37 Wear suitable protective clothing and gloves. 
S60 This material and its container must be disposed of as hazardous waste. 
S61 Avoid release to the environment. Refer to special instructions/safety data sheets.
Attentions:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Standards and Recommendations：

 

Analytical Methods：