CAS No.:42397-65-9
Name: 1,8-Dinitropyrene
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
mmo-sat 1 nmol/plate |
SCIEAS Science. 209 (1980),1039. | ||
2. |
mma-sat 1 µg/plate |
MUREAV Mutation Research. 91 (1981),321. | ||
3. |
msc-hmn:lym 100 µg/L |
ENMUDM Environmental Mutagenesis. 5 (1983),457. | ||
4. |
msc-mus:lym 500 µg/L |
EVSRBT Environmental Science Research. 25 (1982),397. |
Consensus Reports:
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 231.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 231.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 231.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Confirmed carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: Xn
Risk Statements: 40
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 22-26-36/37
S22: Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37: Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS: UR2456000
Standards and Recommendations:
DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans
Analytical Methods:
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