CAS No.:2530-99-6

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TDLo	oral	26mg/kg (26mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 113, 1946.
mouse	LD50	intraperitoneal	102mg/kg (102mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 116, Pg. 343, 1956.
mouse	LD50	intravenous	40mg/kg (40mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 113, 1946.
mouse	LD50	oral	191mg/kg (191mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 116, Pg. 343, 1956.
mouse	LDLo	subcutaneous	125mg/kg (125mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 25, Pg. 361, 1921.
rabbit	LDLo	intravenous	50mg/kg (50mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: EXCITEMENT	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 25, Pg. 361, 1921.
rabbit	LDLo	subcutaneous	100mg/kg (100mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 25, Pg. 361, 1921.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, subcutaneous, intraperitoneal and intravenous routes. Human systemic effects by ingestion: changes in motor activity and nausea or vomiting. When heated to decomposition it emits highly toxic NO_x.

Standards and Recommendations：

 

Analytical Methods：