CAS No.:113-18-8

TOXICITY DATA with REFERENCE：

1.		orl-wmn TDLo:10 mg/kg:CNS		BMJOAE    British Medical Journal. 2 (1962),1610.
2.		orl-wmn TDLo:15 mg/kg/2D:BLD		AIMEAS    Annals of Internal Medicine. 77 (1972),73.
3.		scu-rat LD50:200 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
4.		orl-mus LD50:290 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 114 (1955),326.
5.		ipr-mus LD50:275 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
6.		scu-mus LD50:240 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 114 (1955),326.
7.		ivn-dog LD50:55 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,420.
8.		orl-bwd LD50:42 mg/kg		TXAPA9    Toxicology and Applied Pharmacology. 21 (1972),315.

SAFETY PROFILE：
Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: general anesthesia and thrombocytopenia (reduction in the number of blood platelets). Human effects on newborn by an unspecified route: drug dependency and Apgar score (condition of newborn). Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻.