CAS No.:316-42-7
Name: 1-Emetine dihydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
eye-hmn 3250 µg |
BJIMAG British Journal of Industrial Medicine. 4 (1947),111. | ||
2. |
scu-wmn LDLo:2770 µg/kg/4D-I:BAH,GIT |
AIMDAP Archives of Internal Medicine. 17 (1916),420. | ||
3. |
scu-man LDLo:25 mg/kg/20D-I:GIT.PUL |
AIMDAP Archives of Internal Medicine. 17 (1916),420. | ||
4. |
orl-rat LD50:12 µg/kg |
ANTCAO Antibiotics and Chemotherapy. 8 (1958),297. | ||
5. |
ipr-rat LD50:17 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 94 (1948),431. | ||
6. |
orl-mus LD50:15 µg/kg |
ANTCAO Antibiotics and Chemotherapy. 8 (1958),297. | ||
7. |
ipr-mus LD50:62 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 94 (1948),431. | ||
8. |
scu-mus LD50:37 mg/kg |
JPPMAB Journal of Pharmacy and Pharmacology. 16 (1964),65. | ||
9. |
scu-mky LDLo:13,886 µg/kg |
IMGAAY Indian Medical Gazette. 49 (1914),85. | ||
10. |
orl-cat LDLo:15 mg/kg |
AJTMAQ American Journal of Tropical Medicine. 10 (1930),249. | ||
1 |
Consensus Reports:
EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.
SAFETY PROFILE:
A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: diarrhea, distorted perceptions, dyspnea, hallucinations, hypermotility, nausea or vomiting. A human eye irritant. When heated to decomposition it emits very toxic fumes of Cl− and NOx.Safety information of 1-Emetine dihydrochloride (CAS NO.316-42-7):
Hazard Codes T+
Risk Statements
28 Very Toxic if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/37 Wear suitable protective clothing and gloves
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 1544 6.1/PG 1
WGK Germany 3
RTECS JY5250000
F 3-8-10
HazardClass 6.1(a)
PackingGroup I
Standards and Recommendations:
Analytical Methods:
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