CAS No.:6893-24-9
Name: 1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE
Details Introduction
TOXICITY DATA with REFERENCEļ¼Its side effect profile is similar to haloperidol, namely predominantly dopamine-blocking effects which give rise to akathisia, parkinsonism and tremor. Long term side effects include the potentially irreversible tardive dyskinesia and the potentially fatal neuroleptic malignant syndrome.
SAFETY PROFILEļ¼
Notable side effects include akathisia, extrapyramidal side effects, including tardive dyskinesia and Rabbit syndrome. The frequency and severity of extrapyramidal side effects are direct proportional to the dose given and the duration of treatment.
Sedative, allergic-toxic and anticholinergic/sympatholytic side effects are less likely to occur compared with chlorpromazine. The direct deposition of fluphenazine in the cornea and retina has so far not been reported.
Neuroleptic malignant syndrome, although rare, is a potentially lethal side effect of all antipsychotics.
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