CAS No.:23007-85-4
Name: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 150mg/kg (150mg/kg) | Annales Pharmaceutiques Francaises. Vol. 12, Pg. 241, 1954. | |
mouse | LD50 | subcutaneous | 53800ug/kg (53.8mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Journal of Pharmacology and Experimental Therapeutics. Vol. 247, Pg. 531, 1988. |
rat | LD50 | intraperitoneal | 72mg/kg (72mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Bulletin of Experimental Biology and Medicine Vol. 105, Pg. 470, 1988. |
Consensus Reports:
SAFETY PROFILE:
A poison by intraperitoneal and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and Cl−.
Hazard Codes T
Risk Statements 39-23/24/25
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R39:Danger of very serious irreversible effects.
Safety Statements 45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS UT8358950
HazardClass 6.1(b)
PackingGroup III
Standards and Recommendations:
Analytical Methods:
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