CAS No.:7519-36-0
Name: 1-Nitrosopyrrolidine-2-carboxylic acid
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 203mg/kg (203mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES |
Journal of Medicinal Chemistry. Vol. 16, Pg. 583, 1973. |
Consensus Reports：
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE：
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Many nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also NITROSO COMPOUNDS.
Standards and Recommendations：
Analytical Methods：
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