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Current position:Home > Products > 10-METHYLPHENOTHIAZINE-2-ACETIC ACID

CAS No.:13993-65-2

Name: 10-METHYLPHENOTHIAZINE-2-ACETIC ACID

Details Introduction

TOXICITY DATA with REFERENCEļ¼š

1.   

orl-rat LD50:495 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),822.
2.   

ipr-rat LD50:365 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),429.
3.   

scu-rat LD50:405 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),107.
4.   

orl-mus LD50:800 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1198.
5.   

ipr-mus LD50:350 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),429.
6.   

scu-mus LD50:490 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1207.
7.   

ivn-mus LD50:350 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1198.
8.   

orl-dog LD50:2000 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1207.
9.   

orl-gpg LD50:225 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1207.

SAFETY PROFILEļ¼š
Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Experimental reproductive effects. An anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of SOx and NOx.

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