CAS No.:897-15-4

TOXICITY DATA with REFERENCE：

1.		orl-rat TDLo:440 mg/kg (MGN):REP		OYYAA2    Oyo Yakuri. Pharmacometrics. 27 (1984),1103.
2.		orl-wmn LDLo:40 mg/kg		PGMJAO    Postgraduate Medical Journal. 60 (1984),442.
3.		orl-cld TDLo:90 mg/kg:CVS		PGMJAO    Postgraduate Medical Journal. 60 (1984),442.
4.		orl-rat LD50:260 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
5.		ipr-rat LD50:105 mg/kg		IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 14 (1983),192.
6.		scu-rat LD50:760 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
7.		ivn-rat LD50:24 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
8.		orl-mus LD50:209 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,88.
9.		ipr-mus LD50:116 mg/kg		IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 14 (1983),192.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Human systemic effects by ingestion: cardiomyopathy. Experimental teratogenic and reproductive effects. An antidepressant. When heated to decomposition it emits very toxic fumes of NO_x, SO_x and HCl.

Standards and Recommendations：

 

Analytical Methods：