CAS No.:7242-07-1
Name: 16-Acetylgitoxin
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | intraperitoneal | 148ug/kg (0.148mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965. | |
cat | LD50 | intravenous | 610ug/kg (0.61mg/kg) | "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 187, 1963. | |
cat | LD50 | oral | 120ug/kg (0.12mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 159, Pg. 1, 1966. | |
guinea pig | LD50 | oral | 2500ug/kg (2.5mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 159, Pg. 1, 1966. | |
mouse | LD50 | intraperitoneal | 6800ug/kg (6.8mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965. | |
rat | LD50 | intravenous | 16500ug/kg (16.5mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 165, 1965. |
Consensus Reports:
SAFETY PROFILE:
Deadly poison by ingestion, intraperitoneal and intravenous routes. When heated to decomposition it emits acrid smoke and fumes. See also GITOXIN.
Standards and Recommendations:
Analytical Methods:
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