CAS No.:56-10-0

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intraperitoneal	113mg/kg (113mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 142, Pg. 510, 1963.
dog	LD50	oral	177mg/kg (177mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 142, Pg. 510, 1963.
guinea pig	LD50	intraperitoneal	356mg/kg (356mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 129, Pg. 218, 1960.
mouse	LD50	intraperitoneal	400mg/kg (400mg/kg)		National Technical Information Service. Vol. AD277-689,
mouse	LD50	intravenous	85400ug/kg (85.4mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 129, Pg. 218, 1960.
mouse	LD50	oral	815mg/kg (815mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 129, Pg. 218, 1960.
mouse	LD50	subcutaneous	242mg/kg (242mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 576, 1957.
rabbit	LD50	intraperitoneal	236mg/kg (236mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 142, Pg. 510, 1963.
rat	LD50	intraperitoneal	288mg/kg (288mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 142, Pg. 198, 1963.
rat	LD50	intravenous	85mg/kg (85mg/kg)		Casopis Lekaru Ceskych. Journal of Czech Physicians. Vol. 105, Pg. 1165, 1966.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Antiradon (CAS NO.56-10-0):
Hazard Codes: Xn
Risk Statements: 22-36/37/38 
22:  Harmful if swallowed 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 26-36/37-22
22:  Do not breathe dust 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 

Standards and Recommendations：

 

Analytical Methods：