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Current position:Home > Products > 2,12-DIHYDROXY-4-METHYL-11,16-DIOXOSENECIONANIUM

CAS No.:2318-18-5

Name: 2,12-DIHYDROXY-4-METHYL-11,16-DIOXOSENECIONANIUM

Details Introduction

TOXICITY DATA with REFERENCE:

1.   

mma-sat 1 mg/plate

    MUREAV    Mutation Research. 68 (1979),211.
2.   

sln-dmg-orl 10 µmol/L/3D-I

    FCTOD7    Food and Chemical Toxicology. 22 (1984),223.
3.   

dns-rat:lvr 2 µmol/L

    CNREA8    Cancer Research. 45 (1985),3125.
4.   

dns-mus:lvr 20 µmol/L

    CNREA8    Cancer Research. 45 (1985),3125.
5.   

dns-ham:lvr 2 µmol/L

    CNREA8    Cancer Research. 45 (1985),3125.
6.   

sce-ham:lng 60 µg/L

    MUREAV    Mutation Research. 142 (1985),209.
7.   

orl-rat LDLo:200 mg/kg

    NATUAS    Nature. 227 (1970),401.
8.   

ipr-rat LD50:220 mg/kg

    JJIND8    JNCI, Journal of the National Cancer Institute. 63 (1979),469.

Consensus Reports:IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 ,1983,p. 231.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 ,1976,p. 327.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

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