CAS No.:2318-18-5
Name: 2,12-DIHYDROXY-4-METHYL-11,16-DIOXOSENECIONANIUM
Details Introduction
TOXICITY DATA with REFERENCE:
1. | mma-sat 1 mg/plate | MUREAV Mutation Research. 68 (1979),211. | ||
2. | sln-dmg-orl 10 µmol/L/3D-I | FCTOD7 Food and Chemical Toxicology. 22 (1984),223. | ||
3. | dns-rat:lvr 2 µmol/L | CNREA8 Cancer Research. 45 (1985),3125. | ||
4. | dns-mus:lvr 20 µmol/L | CNREA8 Cancer Research. 45 (1985),3125. | ||
5. | dns-ham:lvr 2 µmol/L | CNREA8 Cancer Research. 45 (1985),3125. | ||
6. | sce-ham:lng 60 µg/L | MUREAV Mutation Research. 142 (1985),209. | ||
7. | orl-rat LDLo:200 mg/kg | NATUAS Nature. 227 (1970),401. | ||
8. | ipr-rat LD50:220 mg/kg | JJIND8 JNCI, Journal of the National Cancer Institute. 63 (1979),469. |
Consensus Reports:IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 ,1983,p. 231.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 ,1976,p. 327.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
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